OrganisationHow It Works

How It Works: Why the Concentration Gradient Is Everything

Part of Gas Exchange in HumansGCSE Biology

This how it works covers How It Works: Why the Concentration Gradient Is Everything within Gas Exchange in Humans for GCSE Biology. Lung structure, alveoli adaptations, breathing mechanism, gas transport in blood, and effects of smoking It is section 11 of 19 in this topic. Use this how it works to connect the idea to the wider topic before moving on to questions and flashcards.

Topic position

Section 11 of 19

Practice

19 questions

Recall

23 flashcards

How It Works: Why the Concentration Gradient Is Everything

Gas exchange at the alveolus is driven entirely by diffusion, which means it can only happen when there is a concentration gradient — a difference in concentration of a gas on either side of the alveolar membrane. The moment that gradient disappears, gas exchange stops.

In the alveolus, oxygen concentration is kept high because you constantly breathe in fresh air. In the blood arriving at the alveolus (from the pulmonary artery), oxygen concentration is low because it has already been used up by respiring body cells. This difference is the gradient that drives oxygen to diffuse from the alveolus into the blood.

For carbon dioxide it is the reverse: blood arriving at the alveolus carries a high concentration of CO₂ (produced by cellular respiration), while the alveolar air has a low CO₂ concentration (you exhale CO₂ with every breath). So CO₂ diffuses from blood into the alveolar air space, and is breathed out.

The dense capillary network is critical for maintaining these gradients. Blood flows continuously past the alveolus — it is constantly being refreshed, taking away the oxygen it has collected and delivering new CO₂. Without this continuous blood flow, both gradients would collapse and gas exchange would cease. This is why poor circulation is just as dangerous as poor breathing.

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Practice Questions for Gas Exchange in Humans

Which is the correct order of structures air passes through to reach the lungs?

  • A. Trachea → bronchi → bronchioles → alveoli
  • B. Bronchi → trachea → bronchioles → alveoli
  • C. Trachea → bronchioles → bronchi → alveoli
  • D. Bronchioles → bronchi → trachea → alveoli
1 markfoundation

Explain how the structure of alveoli is adapted for efficient gas exchange.

4 marksstandard

Quick Recall Flashcards

What are alveoli?
Tiny air sacs in the lungs where gas exchange takes place - oxygen enters the blood and carbon dioxide leaves
What is the trachea?
The main airway (windpipe) that carries air from the throat to the lungs, reinforced with cartilage rings

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