This exam focus covers Exam Focus within Glucose Regulation for GCSE Biology. Topic 6: Glucose Regulation It is section 13 of 15 in this topic. Treat this as a marking guide for what examiners are looking for, not just a fact list.
Topic position
Section 13 of 15
Practice
15 questions
Recall
20 flashcards
Exam Focus
Exam Favourite — AQA Paper 2Appears in 3 out of 5 recent AQA Paper 2 sittings — this is a VERY HIGH priority topic. Earns 4–8 marks per appearance. Extended response questions are common.
Typical question types:
- "Describe the role of insulin in controlling blood glucose." (3 marks)
- "Explain how the body responds when blood glucose rises after a meal." (4 marks)
- "Compare Type 1 and Type 2 diabetes in terms of cause, affected cells, and treatment." (4–6 marks)
- "Explain why exercise causes blood glucose to fall." (3 marks)
- Graph interpretation: given a blood glucose curve, identify the point of insulin release and explain what causes each feature.
What examiners look for at each level:
- 1–2 marks: Name insulin (lowers glucose) and glucagon (raises glucose); identify that the pancreas secretes them.
- 3–4 marks: Explain the negative feedback loop with both hormones — describe what triggers each hormone, where it acts, and the result. Link glucose → glycogen (insulin) and glycogen → glucose (glucagon).
- 5–6 marks: Link storage to glycogen in liver/muscle; name alpha cells (glucagon) and beta cells (insulin); explain both types of diabetes with their specific cause and treatment; show the loop completes (secretion drops once glucose returns to normal).
Common mistakes that lose marks:
- Confusing insulin and glucagon — insulin LOWERS blood glucose; glucagon RAISES it. Writing the wrong direction always loses marks.
- Forgetting to mention glycogen as the storage molecule — "glucose is stored" without naming glycogen is incomplete.
- Saying "Type 1 diabetes is caused by eating too much sugar" — it is an autoimmune condition; the immune system destroys beta cells. Diet does not cause Type 1.
- Not linking exercise to increased glucose uptake by muscle cells — exercise increases respiration in muscles, which uses up more glucose from the blood, lowering blood glucose concentration.
- Describing only insulin and ignoring glucagon (or vice versa) on comparison questions.