Key Facts and Numbers to Know

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๐Ÿ“‹ Key Facts and Numbers to Know

  • Normal core body temperature: 37ยฐC (the optimum for most human enzymes)
  • Normal blood glucose range: approximately 4โ€“8 mmol/L (rises after meals, falls during exercise, then corrected)
  • Normal blood pH range: 7.35โ€“7.45 (maintained largely by the lungs and kidneys)
  • The three main variables controlled: temperature, blood glucose, water balance
  • Every control system has the same three components: receptor โ†’ coordination centre โ†’ effector
  • Negative feedback responses are always opposite in direction to the original change
  • The nervous system is faster but shorter-lived; the endocrine system is slower but longer-lasting
  • Enzymes denature at temperatures significantly above 37ยฐC โ€” the active site changes shape permanently
  • Different coordination centres handle different variables: hypothalamus (temperature), pancreas (blood glucose), kidneys (water balance)

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