Cell BiologyExam Focus

Exam Focus: 6-Mark "Evaluate the Use of Stem Cells in Medicine"

Part of Stem Cells and Cell DifferentiationGCSE Biology

This exam focus covers Exam Focus: 6-Mark "Evaluate the Use of Stem Cells in Medicine" within Stem Cells and Cell Differentiation for GCSE Biology. Stem cell types, differentiation processes, therapeutic applications, embryonic vs adult stem cells, and ethical considerations It is section 14 of 16 in this topic. Treat this as a marking guide for what examiners are looking for, not just a fact list.

Topic position

Section 14 of 16

Practice

20 questions

Recall

25 flashcards

📝 Exam Focus: 6-Mark "Evaluate the Use of Stem Cells in Medicine"

This is one of the most frequently set 6-mark extended response questions for this topic. Examiners want a balanced evaluation — arguments for AND arguments against, with a conclusion.

Arguments FOR using stem cells in medicine:

  • Can potentially cure or treat diseases that are currently incurable (e.g., Parkinson's disease, type 1 diabetes, spinal cord injuries)
  • Can replace damaged or diseased tissue with healthy, functional cells
  • Adult stem cells (e.g., from bone marrow) can be taken from the patient's own body, reducing the risk of immune rejection
  • Existing treatments (bone marrow transplants, skin grafts) have already saved many lives
  • iPSCs (induced pluripotent stem cells) can be produced from adult cells, avoiding the ethical issues associated with embryos

Arguments AGAINST using stem cells in medicine:

  • Ethical concerns: Embryonic stem cells are obtained by destroying a human embryo, which many people consider to be a human life
  • Immune rejection risk: If stem cells come from a donor rather than the patient, the immune system may attack them
  • Tumour risk: Stem cells that divide uncontrollably could form tumours (particularly a risk with pluripotent cells)
  • Technical challenges: Controlling differentiation precisely is very difficult; cells may not differentiate into the desired type
  • Many potential treatments are still experimental and not yet proven safe or effective in humans

Top tip for 6 marks: Present at least two points on each side, use scientific terminology, and end with a brief conclusion that weighs up the arguments. Do not just list points — try to explain why each point matters.

Keep building this topic

Read this section alongside the surrounding pages in Stem Cells and Cell Differentiation. That gives you the full topic sequence instead of a single isolated revision point.

Practice Questions for Stem Cells and Cell Differentiation

What is a stem cell?

  • A. An undifferentiated cell that can divide to produce many cell types
  • B. A specialized cell found only in plant roots
  • C. A cell that has already differentiated into a nerve cell
  • D. A bacterial cell that divides by binary fission
1 markfoundation

Explain how sperm cells are adapted for their function.

3 marksstandard

Quick Recall Flashcards

What does 'totipotent' mean?
The highest level of potency - cells can differentiate into any cell type in the organism plus extraembryonic tissues like the placenta. Example: fertilized egg.
What is a stem cell?
An undifferentiated cell that can divide to produce more stem cells (self-renewal) or differentiate into specialized cell types.

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