Infection & ResponseKey Facts

Advantages of Monoclonal Over Polyclonal Antibodies

Part of Monoclonal AntibodiesGCSE Biology

This key facts covers Advantages of Monoclonal Over Polyclonal Antibodies within Monoclonal Antibodies for GCSE Biology. Production and medical applications of identical antibodies, hybridoma cells, diagnostics It is section 7 of 17 in this topic. Use this key facts to connect the idea to the wider topic before moving on to questions and flashcards.

Topic position

Section 7 of 17

Practice

15 questions

Recall

18 flashcards

Advantages of Monoclonal Over Polyclonal Antibodies

Characteristic Monoclonal Polyclonal
Specificity Very high - one epitope only Lower - multiple epitopes
Consistency Always identical Varies between animals
Supply Unlimited production Limited by animal lifespan
Contamination Pure - single clone Mixed - many clones
Cost (long-term) Lower - mass production Higher - need animals
Sensitivity Lower - single binding site Higher - multiple sites

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Practice Questions for Monoclonal Antibodies

What does the term 'monoclonal antibody' mean?

  • A. Identical antibodies produced from a single clone of cells
  • B. Antibodies that target many different antigens
  • C. Antibodies produced by many different cells
  • D. Antibodies that come from multiple animal species
1 markfoundation

Explain why hybridoma cells are needed to produce monoclonal antibodies.

3 marksstandard

Quick Recall Flashcards

What is hCG?
Human chorionic gonadotrophin - a hormone only produced during pregnancy, detected by pregnancy tests
What are myeloma cells?
Immortal cancer cells that divide continuously and are used to create hybridoma cells

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