Monoclonal Antibody Production Flowchart

Part of Monoclonal Antibodies · Section 4 of 17

DiagramUnit: Infection & ResponseGCSE

This diagram covers Monoclonal Antibody Production Flowchart within Monoclonal Antibodies for GCSE Biology. Production and medical applications of identical antibodies, hybridoma cells, diagnostics It is section 4 of 17 in this topic. Focus on the labels, the relationships between parts, and the explanation that turns the diagram into an exam-ready answer.

Monoclonal Antibody Production Flowchart

Painted 5-panel sequence showing monoclonal antibody production: (1) mouse injected with antigen, (2) B-cells collected from spleen, (3) B-cell fused with myeloma cell to form hybridoma, (4) selection and cloning of successful hybridomas, (5) mass production in a bioreactor yielding unlimited identical antibodies. Below the panels, a parchment summary states that monoclonal means from one clone and lists uses in pregnancy tests, cancer treatment, and diagnostic tests. Mouse Injected with antigen B cells Make antibodies but die quickly Myeloma cells Immortal cancer cells divide forever FUSION Hybridoma cells Immortal + make antibodies Selection & Cloning Mass Production Unlimited identical antibodies Monoclonal antibodies (all identical)

Practice questions for Monoclonal Antibodies

What does the term 'monoclonal antibody' mean?

  • A. Identical antibodies produced from a single clone of cells
  • B. Antibodies that target many different antigens
  • C. Antibodies produced by many different cells
  • D. Antibodies that come from multiple animal species
1 markfoundation

Explain why hybridoma cells are needed to produce monoclonal antibodies.

3 marksstandard

Quick recall flashcards

What are myeloma cells?
Immortal cancer cells that divide continuously and are used to create hybridoma cells
What is hCG?
Human chorionic gonadotrophin - a hormone only produced during pregnancy, detected by pregnancy tests

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