The Heart and Circulation

BiologyAQAEdexcelGCSEUnit: Organisation
Free taster
5 of 6 sections open
The basics

The Heart: Your Body's Tireless Pump

🫀 The Heart: Your Body's Tireless Pump

Every minute of your life, your heart beats about 70 times, pumping 5 litres of blood around your body. In just one day, your heart will beat over 100,000 times and pump enough blood to fill a small swimming pool. This incredible muscle never rests, working 24/7 to deliver oxygen and nutrients to every cell in your body.

The story of circulation began when early scientists noticed that blood seemed to "flow" rather than just sit still in vessels. William Harvey's revolutionary experiments in the 1600s proved that blood circulates in a closed loop, powered by the heart as a muscular pump. Today, we know the heart and circulation system is one of the most sophisticated delivery networks on Earth.

Hotspot diagram

The human heart in frontal cross-section. Tap any label to explore that structure in detail.

Cross-section of the human heart showing all four chambers, the aorta, pulmonary artery, and bicuspid valve
  1. 1
    AortaCarries oxygenated blood from the left ventricle to the whole body.
  2. 2
    Pulmonary arteryCarries deoxygenated blood from the right ventricle to the lungs.
  3. 3
    Right atriumReceives deoxygenated blood from the body via the vena cava.
  4. 4
    Right ventriclePumps deoxygenated blood to the lungs. Thinner wall than the left ventricle.
  5. 5
    Left atriumReceives oxygenated blood from the lungs via the pulmonary veins.
  6. 6
    Left ventricleThe most powerful pump. Thick muscular wall pushes blood to the whole body.
  7. 7
    Bicuspid valvePrevents blood flowing back from the left ventricle into the left atrium.

Figure 1: The human heart in frontal cross-section. Tap any label to explore that structure in detail.

Spotlight
The Cardiac Cycle: How Your Heart Beats

Cardiac Output = Heart Rate × Stroke Volume

💡 Four-chamber heart structure
Exam tip

Earn the mark scheme marks

Memory Aids

Complete blood flow path — use this mnemonic:

"Very Rich Royals Prefer Luxury Palaces, Lovely Architecture"

  • Vena cava
  • Right atrium
  • Right ventricle
  • Pulmonary artery (to lungs)
  • Lungs (oxygenation)
  • Pulmonary vein (from lungs)
  • Left atrium
  • Aorta (from left ventricle to body)

Artery vs Vein: Arteries carry blood Away from the heart. Veins carry blood TO (into) the heart — and veins have valves because the pressure is low and blood needs help flowing back up against gravity.

Valve names: Tricuspid has 3 flaps and is on the Right (T and R — both later in the alphabet, like Right). Bicuspid has 2 flaps and is on the Left.

Cardiac output calculation: CO = HR x SV — "Heart Rate times Stroke Volume gives the output."

Quick Check: A person has a blockage in their coronary arteries, but their heart chambers are constantly filled with blood. Explain why this blockage could still cause the heart to stop working.

Quick Check: During exercise, a person's heart rate increases from 70 to 140 beats per minute and their stroke volume increases from 70 ml to 100 ml. Calculate the cardiac output at rest and during exercise and explain why this increase is important.

Quick Check: Explain why the double circulatory system gives mammals an advantage over fish, which have a single circulatory system.

Now try it yourself

Quiz · Question 1 of 30

How many chambers does the human heart have?

Tap an answer to check it

Revise every Biology topic, free during alpha

The Heart and Circulation is one of 53 topics on PrepWise — all aligned to your exam board.

Start revising free →