Key Facts About Monoclonal Antibodies

Part of Monoclonal Antibodies · Section 2 of 17

Key FactsUnit: Infection & ResponseGCSE

This key facts covers Key Facts About Monoclonal Antibodies within Monoclonal Antibodies for GCSE Biology. Production and medical applications of identical antibodies, hybridoma cells, diagnostics It is section 2 of 17 in this topic. Use this key facts to connect the idea to the wider topic before moving on to questions and flashcards.

Key Facts About Monoclonal Antibodies

  • Monoclonal = from a single clone of cells, producing identical antibodies
  • Polyclonal = from many different clones, producing varied antibodies
  • All monoclonal antibodies are specific to one antigen
  • Made using hybridoma cells (fusion of B cell + immortal cell)
  • Can be produced in unlimited quantities in laboratories
  • Used in pregnancy tests, cancer treatment, and disease diagnosis

Practice questions for Monoclonal Antibodies

What does the term 'monoclonal antibody' mean?

  • A. Identical antibodies produced from a single clone of cells
  • B. Antibodies that target many different antigens
  • C. Antibodies produced by many different cells
  • D. Antibodies that come from multiple animal species
1 markfoundation

Explain why hybridoma cells are needed to produce monoclonal antibodies.

3 marksstandard

Quick recall flashcards

What are myeloma cells?
Immortal cancer cells that divide continuously and are used to create hybridoma cells
What is hCG?
Human chorionic gonadotrophin - a hormone only produced during pregnancy, detected by pregnancy tests

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