Medicine Through TimeSource Analysis

Source Analysis Practice

Part of PenicillinGCSE History

This source analysis covers Source Analysis Practice within Penicillin for GCSE History. Revise Penicillin in Medicine Through Time for GCSE History with 8 exam-style questions and 4 flashcards. This topic appears less often, but it can still be a useful differentiator on mixed-topic papers. It is section 8 of 14 in this topic. Use this source analysis to connect the idea to the wider topic before moving on to questions and flashcards.

Topic position

Section 8 of 14

Practice

8 questions

Recall

4 flashcards

📜 Source Analysis Practice

"In the first place, I should remark that it is not difficult to make penicillin in the laboratory... but the large-scale preparation is very difficult... I would like to point out, however, that it is advisable to mention the possibility that there may arise drugs of the penicillin type which may be taken by mouth."
— Alexander Fleming, "On the Antibacterial Action of Cultures of a Penicillium, with Special Reference to their Use in the Isolation of B. Influenzae," British Journal of Experimental Pathology, June 1929, Fleming's original published account of his discovery written for a scientific audience

Applying NOP Analysis:

Nature: This is a scientific journal article — a peer-reviewed publication reporting the results of laboratory experiments, written in a formal, technical style for a specialist academic audience of bacteriologists and medical researchers.

Origin: Written by Alexander Fleming in 1929, one year after his accidental discovery of penicillin's antibacterial properties in August 1928. Fleming was a bacteriologist at St Mary's Hospital, London, and was reporting experimental findings while also acknowledging the significant practical difficulties of producing the substance in quantity.

Purpose: To communicate Fleming's experimental findings to the scientific community and invite further research. Fleming was not claiming to have produced a usable drug — he was documenting an observation and suggesting future possibilities, including the potential for drugs taken by mouth.

Grade 9 Model Paragraph:

This source is useful for an enquiry into the development of penicillin because it shows Fleming's honest assessment in 1929 that while the discovery was real, large-scale production was "very difficult" — helping explain why penicillin sat unused for a decade before Florey and Chain took up the challenge in 1939. As Fleming's own published research, it provides direct evidence of his thinking and the technical obstacles he identified. However, its utility is limited because the article was written for specialist scientists, not policymakers, meaning it had no immediate impact on medical practice. It also reveals the limits of Fleming's contribution: he identified the phenomenon but could not solve the production problem that Florey and Chain eventually resolved.

Keep building this topic

Read this section alongside the surrounding pages in Penicillin. That gives you the full topic sequence instead of a single isolated revision point.

Practice Questions for Penicillin

In which year did Alexander Fleming discover penicillin?

  • A. 1918
  • B. 1928
  • C. 1939
  • D. 1945
1 markfoundation

Which two scientists purified penicillin and made it usable as a medicine?

  • A. Pasteur and Koch
  • B. Jenner and Lister
  • C. Fleming and Pasteur
  • D. Florey and Chain
1 markfoundation

Quick Recall Flashcards

Who developed penicillin for use?
Howard Florey and Ernst Chain (Oxford, 1939-41)
What is an antibiotic?
A substance produced by a living organism (like the Penicillium mould) that kills bacteria. Penicillin was the first antibiotic — unlike magic bullets, it was natural, not synthetic.

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