Explore: Inside a Synapse

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⚡ Explore: Inside a Synapse

Tap each dot to see how the chemical messenger crosses from one neurone to the next.

Close-up of a synapse showing vesicles in the pre-synaptic terminal, neurotransmitter molecules in the synaptic cleft, and receptor proteins on the post-synaptic membrane

How a synapse works (4 steps):

  1. An electrical impulse arrives at the end of the first neurone (pre-synaptic neurone).
  2. This triggers the release of neurotransmitters from tiny vesicles into the synaptic cleft.
  3. The neurotransmitters diffuse across the gap and bind to specific receptor proteins on the next neurone.
  4. This binding triggers a new electrical impulse in the second neurone (post-synaptic neurone).

Why synapses matter: Synapses ensure signals travel in one direction only (neurotransmitters are only released from the pre-synaptic side). They also allow signals to be amplified, inhibited, or combined from multiple neurones — this is how the brain processes complex information.

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